Schizophrenia and Mood Disorders The New Drug Therapies in Clinical Practice

by ; ;
Format: Paperback
Pub. Date: 2001-10-04
Publisher(s): Hodder Education Publishers
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Summary

This authoritative resource comprehensively covers the use of drug therapies in the treatment of mood disorders and schizophrenia. It is divided into three sections. The first two, Schizophrenia and Depression and Mania give detailed accounts of specific drug therapies, whilst the third section, Key Issues in Clinical Psychopharmacology covers a variety of current topics such as considerations for young, old and pregnant patients, substance misuse and pharmacoeconomics. The inclusion of the most up-to-date knowledge, best practices, and clinical pearls from internationally renowned contributors ensure that this is a critical resource for clinicians prescribing for their patients.

Author Biography

Dr Ruth Allen MBBS MRCPsych: Department of Psychiatry, Royal Free Hospital, London, UK. Dr Daniel Andrews MRCPsych BSc: Honorary Lecturer in Psychiatry, Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, London, UK. Professor A. George Awad MB BCh PhD FRCP(C): Professor Emeritus, University of Toronto; Chief of Psychiatry, Department of Psychiatry, Humber River Regional Hospital, Toronto, Canada. Professor Thomas R.E. Barnes MD FRCPsych: Professor of Clinical Psychiatry, Department of Psychiatry, Imperial College School of Medicine, London, UK. Professor Charles Bowden MD: Chairman, Department of Psychiatry, The University of Texas Health Science Center at San Antonio Dr Robert W. Buchanan MD: Professor of Psychiatry, Maryland Psychiatric Research Center, Baltimore, USA. Dr Peter F. Buckley MD: Professor and Vicechair, Department of Psychiatry, Case Western Reserve University; Medical Director, Northcoast Behavioral Healthcare System, Cleveland, Ohio, USA. Professor Joseph Calabrese MD: Professor of Psychiatry, Director, Mood Disorders Program, University Hospitals, Department of Psychiatry, Case Western Reserve University, Ohio, USA. Professor Daniel Casey MD: Psychiatry Service, Veterans Affairs Medical Center, Oregon, USA. Dr Robert Conley MD: Associate Professor of Psychiatry, Maryland Psychiatric Research Center, Baltimore, USA. Dr John Cookson MD PhD: Consultant Psychiatrist, Psychiatric Department, The Royal London Hospital, St Clements, London, UK. Dr Stephen Cooper MD FRCPsych: Senior Lecturer, Department of Mental Health, The Queen's University of Belfast, N. Ireland. Dr Ruth Dickson MD FRCP(C): Associate Professor, Department of Psychiatry, University of Calgary, Canada. Professor Ted Dinan MD PhD: Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin. Professor Nicol Ferrier MD: Professor of Psychiatry, School of Neuroscience and Psychiatry, University of Newcastle, Newcastle-upon-Tyne, UK. Professor W. Wolfgang Fleischhacker MD: Professor and Head of the Department of Biological Psychiatry, Department of Psychiatry, Innsbruck University Clinics, Austria. Dr Sophia Frangou MD MSc MRCPsych: Senior Lecturer in Psychiatry, Institute of Psychiatry, London, UK. Dr William Glazer MD: Associate Clinical Professor of Psychiatry, Harvard Medical School, Boston, MA, USA. Professor Siegfried Kasper MD: Professor and Chairman, Department of General Psychiatry, University of Vienna, Austria. Professor Cornelius Katona MD FRCPsych: Department of Psychiatry and Behavioural Sciences, Royal Free and UCL Medical School and Essex and Herts Community NHS Trust, London, UK. Professor Paul Keck MD: Professor and Vice Chairman for Research, University of Cincinnati College of Medicine Dr Jeffrey Kelsey MD PhD: Department of Psychiatry, Emory University School of Medicine, Atlanta, Georgia, USA. Professor David King MD FRCPsych FRCP(I) DPM: Professor of Clinical Psychopharmacology, Department of Therapeutics and Pharmacology, Belfast, N. Ireland. Dr Sanjiv Kumra MD, FRCP(C): Center for Addictions and Mental Health and the Hospital for Sick Children, University of Toronto, Canada. Professor Brian Leonard PhD DSc: Pharmacology Department, National University of Ireland, Galway. Professor Shon Lewis MD: Professor of Adult Psychiatry, The University of Manchester, UK. Professor Rasmus W. Licht MD: Chief Psychiatrist and Director of the Mood Disorders Research Unit at the Psychiatric Hospital in Aarhus, Risskov, Denmark; Associate Professor in Clinical Pharmacology at The University of Aarhus, Denmark. Dr Sheila Marcus MD: Director, Adult Ambulatory Division, University of Michigan Health Systems. Professor Stephen R. Marder MD: Professor and Vice Chair, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA. Professor Patrick McGorry MB BS MRCP(UK) FRANZCP PhD: Professor of Psychiatry, University of Melbourne, Victoria, Australia. Dr Peter McKenna MD: Consultant Psychiatrist, Fulbourn Hospital, Cambridge, UK. Professor Kim Mueser PhD: Professor of Psychiatry, Dartmouth Medical School, New Hampshire-Dartmouth Psychiatric Research Center, New Hampshire, USA. Professor Bruno Muller-Oerlinghausen MD: Forschergruppe Klinische Psychopharmakologie, Psychiatrische Klinik und Poliklinik der Freien Universitat Berlin, Germany. Professor Dieter Naber MD: Professor of Psychiatry and Head of Department, Psychiatrische Klinik, Hamburg, Germany. Professor Charles Nemeroff MD PhD: Professor and Chairman, Department of Psychiatry, Emory University School of Medicine, Atlanta, Georgia, USA. Professor Willem A. Nolen MD: Professor of Psychiatry, University Medical Centre Utrecht and H.C. Rumke Groep, Willem Arntsz Huis, Utrecht, The Netherlands. Dr Robert Post MD: Chief, NIMH Biological Pyschiatry Branch Bethesda, Maryland, USA. Professor Steven Potkin MD: Professor, Department of Psychiatry; Director, Clinical Psychiatric Research and Robert R. Sprague Director, Brain Imaging Center, University of California, Irvine Dr Barbora Richardson MBBChir MRCGP MRCPsych: Department of Psychiatry and Behavioural Sciences, Royal Free and UCL Medical School, London, UK. Professor Elliott Richelson MD: Professor of Psychiatry and Pharmacology, Mayo Medical School, Rochester, MN Consultant in Psychiatry and Pharmacology, Mayo Clinic Jacksonville, Florida, USA. Dr Gary Sachs MD: Department of Psychiatry, Massachusetts General Hospital, Boston, USA. Professor Alan Schatzberg MD: Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences, California, USA. Professor S. Charles Schulz MD: Chair, Department of Psychiatry, University of Minnesota, Minneapolis, USA. Dr Tim Stevens MBBCh MRCPsych: Department of Psychiatry and Behavioural Sciences, Royal Free and UCL Medical School and Essex and Herts Community NHS Trust, London, UK. Dr Trisha Suppes MD PhD: University of Texas Southwestern Medical Center, Associate Professor, Department of Psychiatry; Director, Bipolar Disorder Clinic and Research Program; Bipolar Module Director, Texas Medication Algorithm Project (TMAP) Dr Rajiv Tandon MD: Professor of Psychiatry, Department of Psychiatry, University of Michigan Professor Pamela J. Taylor MB BS MRCP FRCPsych: Professor of Special Hospital Psychiatry, Institute of Psychiatry, London, and Broadmoor Hospital, UK. Professor Michael E. Thase MD: Professor of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA. Dr Madhukar Trivedi MD: Associate Professor of Psychiatry, University of Texas Southwestern Medical Center; Director, Depression and Anxiety Disorders Program, and Director, Depression Module Texas Medication Algorithm Project, Southwest Medical Center, Dallas. Professor John Waddington PhD DSc: Professor of Neuroscience, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, Dublin.

Table of Contents

Foreword vii
Preface ix
Contributors x
Section I: Schizophrenia 1(64)
Comparative pharmacology of classical and novel (second-generation) antipsychotics
3(11)
John Waddington
Daniel Casey
Traditional antipsychotic medications: contemporary clinical use
14(7)
Charles Schulz
Patrick McGorry
Clozapine: clinical use and experience
21(11)
Robert Buchanan
Peter McKenna
Risperidone and olanzapine: clinical use and experience
32(10)
Wolfgang Fleischhacker
Stephen Marder
Quetiapine and sertindole: clinical use and experience
42(7)
Peter Buckley
Dieter Naber
Ziprasidone and zotepine: clinical use and experience
49(10)
Steven Potkin
Stephen Cooper
Future directions in novel antipsychotics
59(6)
Robert Conley
Section II: Depression and Mania 65(156)
Synaptic effects of antidepressants: relationships to their therapeutic and adverse effects
67(18)
Brian Leonard
Elliott Richelson
Tricyclic antidepressants and classical monoamine oxidase inhibitors: contemporary clinical use
85(15)
Michael Thase
Willem Nolen
Selective serotonin reuptake inhibitors: clinical use and experience
100(9)
Ted Dinan
Jeffrey Kelsey
Charles Nemeroff
Nefazodone, mirtazapine and venlafaxine: clinical use and experience
109(18)
Madhukar Trivedi
Trisha Suppes
Psychopharmacology of mood stabilizers
127(28)
Robert Post
Lithium: clinical use in mania and prophylaxis of affective disorders
155(24)
John Cookson
Gary Sachs
Carbamazepine and valproate: use in mood disorders
179(11)
Charles Bowden
Bruno Muller-Oerlinghausen
Lamotrigine, gabapentin and the new anticonvulsants: efficacy in mood disorders
190(9)
Nicol Ferrier
Joseph Calabrese
Antipsychotic medications in the treatment of mood disorders
199(13)
Paul Keck
Rasmus Licht
Future directions in novel antidepressants and mood stabilizing agents
212(9)
Siegfried Kasper
Alan Schatzberg
Section III: Key Issues in Clinical Psychopharmacology 221(124)
Drug interactions
223(11)
David King
Psychotropic drugs during pregnancy
234(19)
Sheila Marcus
Rajiv Tandon
Psychopharmacology in the young
253(20)
Sophia Frangou
Sanjiv Kumra
Drug treatment of schizophrenia and mood disorders in older people
273(13)
Ruth Allen
Barbora Richardson
Tim Stevens
Cornelius Katona
Treatment of substance misuse in schizophrenia
286(11)
Kim Mueser
Shon Lewis
Treating violence in the context of psychosis
297(20)
Pamela Taylor
Peter Buckley
Poor compliance with treatment in people with schizophrenia: causes and management
317(13)
Thomas Barnes
Daniel Andrews
A. George Awad
Pharmacoeconomics and resource allocation: lessons from North America
330(15)
William Glazer
Ruth Dickson
Index 345

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