This concise pocketbook provides an easily accessible resource on pulmonary arterial hypertension (PAH) for medical professionals (senior and trainees), nurses and allied disciplines. PAH is not any longer an orphan disease, nor is it associated with a grave prognosis and premature death (as it used to be the case a decade or two ago). Patients with PAH should enjoy improved survival and quality of life, provided that an early -and not late- diagnosis is made combined with timely initiation of advanced therapy in specialized/designated tertiary centres. This comprehensive text incorporates PAH expertise from the UK and the rest of the world. The book outlines the key points with respect to the latest classification, pathobiology, genetics, clinical assessment of the patient with suspected PAH and the role of imaging. There are specific chapters addressing different PAH aetiologies, namely idiopathic PAH, thromboembolic PAH, PAH related to connective tissue disease, congenital heart disease (Eisenmenger complex), respiratory disease and other unusual causes. Last, but not least, the book addresses counselling, contraception and the latest therapy for the challenging area of pregnancy and PAH, which is still associated with a high maternal mortality risk. The main objective of the book is to increase awareness of PAH, promote rapid diagnostic work up and timely specialist referral so that effective therapy is made available as early as possible to all patients with suspected or known PAH. Physicians -senior or Junior, nurse or other health care professional - whether senior or junior - who may encounter patients with PAH has much to gain from this book.

Michael A. Gatzoulis, MD, PhD, is the Academic Head of the Adult Congenital Heart Centre and Centre for Pulmonary Arterial Hypertension at the Royal Brompton Hospital and the Professor of Cardiology, Congenital Heart Disease at the NHLI, Imperial College, London. Professor Gatzoulis has edited, co-edited or served as a Section Editor for several cardiology and other textbooks (including the reference text Diagnosis and Management of Adult Congenital Heart Disease and the Thorax Section of the 40th Edition of Gray's Anatomy) and authored over 200 peer-reviewed publications. He has been a Visiting Professor in a number of institutions worldwide, including Harvard, Stanford, Montreal Heart, the University of Athens and the Japanese Circulation Society, and served as President of the International Society for Adult Congenital Cardiac Disease, the largest relevant professional body in the world. His main interest is to promote the needs of CHD patients across the world and support education.

1. Classifi cation of pulmonary arterial hypertension and current therapeutic approach, Michael Gatzoulis and Natalie Chung
2. Pathobiology of pulmonary arterial hypertension, Martin Wilkins, Lan Zhao, Chien-Nien Chen and Zhenguo Zhai
3. Genetics, Richard Trembath
4. Clinical assessment of the patient with suspected PAH and the role of cardiac catherization, Mike Landzberg
5. Imaging of pulmonary arterial hypertension, Craig Broberg and Mark Hiatt
6. Idiopathic pulmonary arterial hypertension, Andrew Peacock and Stephen Crawley
7. Chronic thromboembolic pulmonary hypertension (CTEPH), Joanna Pepke-Zaba, Nick Morrell, Karen Sheares and David Jenkins
8. Connective tissue disease associated pulmonary arterial hypertension, Gerry Coghlan
9. Eisenmenger complex, Konstantinos Dimopoulos and Georgios Giannakoulas
10. Respiratory causes of pulmonary hypertension, John Wort and Tamera Corte
11. Other causes of pulmonary arterial hypertension, Sara Goletto and Ryo Inozuka
12. Pregnancy and pulmonary arterial hypertension, Elizabeth Bedard