| Dedication: A Tribute to Dr. Horacio Cingolani |
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xi | |
| Preface |
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xiii | |
| Acknowledgments |
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xvii | |
| I. CELLULAR PROCESSES INVOLVED IN HEART DYSFUNCTION |
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1 | (200) |
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3 | (20) |
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KARL WERDAN, HENDRIK B. SCHMIDT, FRITHJOF SCHLEGEL, ANJA HERKLOTZ, AND URSULA MUELLER-WERDAN |
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2. Mitochondrial Function-A Limiting Factor in Heart Failure? |
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23 | (12) |
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3. Myosin Heavy Chain Isoforms Modulate Motor Function of Cardiac Myosin by Changing Crossbridge Kinetics |
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35 | (16) |
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HIROSHI YAMASHITA, SEIRYO SUGIURA, HIDEO FUJITA, SOICHIRO YASUDA, RYOZO NAGAI, YASUTAKE SAEKI, AND HARDO SUCI |
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4. Role of Reactive Oxygen Species in the Regulation of Cardiac Myocyte Phenotype |
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51 | (8) |
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MELANIE MAYTIN, DOUGLAS B. SAWYER, AND WILSON S. COLUCCI |
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5. Functional Significance of Ryanodine Receptor-Mediated Calcium Leaks in Sarcoplasmic Reticulum Membranes |
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59 | (22) |
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PENELOPE RAMPERSAD, MARK MUTAWE, BERNARD ABRENICA, TOM COOK, AND JAMES GILCHRIST |
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6. Cell-Cell and Cell-Extracellular Matrix Interactions in Cardiomyopathy |
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81 | (6) |
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SHUNZO ONISHI, NAOMASA KAWAGUCHI, SOIJI MORI, AND NARIAKI MATSUURA |
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7. Role of the Phosphoinositide 3-Kinase Pathway in Cardiac Hypertrophy |
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87 | (14) |
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TETSUO SHIOI, JULIE R. MCMULLEN, AND SEIGO IZUMO |
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8. Role of Ras/GTPase and Calcium/Calmodulin-dependent Protein Kinase II in the Signal Transduction Mechanisms Involved in Hyperthermic Preconditioning |
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101 | (8) |
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IBRAHIM F. BENTER, JASBIR S. JUGGI, AND SAGHIR AKHTAR |
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9. Interactions of the Cyclic AMP and Nitric Oxide Pathways in Cardiac Fibroblasts |
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109 | (16) |
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ÅSA B. GUSTAFSSON AND LAURENCE L. BRUNTON |
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10. Do Humoral and Mechanical Stimulation of Cardiomyocyten Share Common Transduction Pathways? |
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125 | (12) |
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ARIE PINSON AND REGINE TIROSH |
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11. Differential Inhibition by the Phosphatase Inhibitor Cantharidin of the Antiadrenergic Effect of Endothelin-1 and Carbachol in the Canine Ventricular Myocardium |
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137 | (16) |
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MASAO ENDON, LI CHU, IKUO NOROTA, AND KUNIAKI ISHII |
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12. Factors Involved in Self and Drug-Induced Spontaneous Ventricular Defibrillation: Intra and Inter Species Variations |
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153 | (14) |
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MORDECHAI MANOACH, NARCIS TRIBULOVA, AND THOMAS PODZUWEIT |
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13. Cardiac ATP-Sensitive Potassium Channel: A Bi-Functional Channel/Enzyme Multimer |
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167 | (14) |
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ALEXEY E. ALEKSEEV, MARTIN BIENENGRAEBER, LEONID V ZINGMAN, PETRAS P. DZEJA, AND ANDRE TERZIC |
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14. Measurement of Cytosolic pH Simultaneously with Isometric Tension in Canine Trabeculae |
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181 | (20) |
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ANTONIO GUIA AND RATNA BOSE |
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| II. PATHOGENESIS OF ISCHEMIC HEART DISEASE |
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201 | (126) |
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15. Redox Regulation of Ischemic Heart Disease |
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203 | (20) |
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16. Cell Biology of Acute Reperfusion Injury |
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223 | (6) |
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CLAUDIA SCHÄFER AND HANS-MICHAEL PIPER |
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17. Reactive Oxygen Species, Na+/H+ Exchange and Cat+ Overload During Myocardial Ischemic/Reperfusion Injury: The Paradox Explained? |
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229 | (10) |
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EMILY C. ROTHSTEIN AND PAMELA A. LUCCHESI |
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18. Calcium Signalling During Acute Myocardial Ischemia: New Insights From Optical Mapping Techniques |
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239 | (18) |
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19. Effects of Ischemia on Cardiomyocyte Connexin-43 Distribution and Phosphorylation Studied in in vivo and in vitro Models |
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257 | (12) |
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STÉPHANE TANGUY, MADHUMATHY JEYARAMAN, BRADLEY W. DOBLE, ZHISHENG JIANG, ROBERT R. FANDRICH, AND ELISSAVET KARDAMI |
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20. Temperature Dependence of Ischemic Preconditioning |
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269 | (8) |
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J.S. JUGGI, E.A.R. GHADHANFAR, M. BARAL-NIETO, AND S. JOSEPH |
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21. Mechanism of Cardioprotective Effect of Remote Aortic Preconditioning |
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277 | (10) |
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MANJEET SINGH AND AJAY SHARMA |
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22. Inhibition of Degranulation of Resident Cardiac Mast Cells May Prevent Ischaemia and Reperfusion-Induced Myocardial Injury |
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287 | (16) |
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MANJEET SINGH AND HARJUT K. SAINI |
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23. Mechanisms of Cardioprotection against Ischemia Reperfusion Injury |
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303 | (24) |
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RAJA B. SINGH AND NARANJAN S. DHALLA |
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| III. THE CELLULAR BASIS FOR VASCULAR DISEASE |
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327 | (144) |
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24. Modulation of Arachidonic Acid Metabolism by Phorbol 12-Myristate 13-Acetate in Monocytes and Myocytes |
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329 | (12) |
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BIRO LU AND PATRICK C. CHOY |
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25. Endothelium-Derived Hyperpolarizing Factor(s). Does it Exist and What Role Does it Play in the Regulation of Blood Flow? |
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341 | (8) |
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CHRIS R. TRIGGLE, MALARVANNAN PANNIRSELVAM, TODD J. ANDERSON, AND HONG DING |
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26. Cytokinesis in Smooth Muscle |
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349 | (12) |
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27. ADP-Ribosylation and the Cardiovascular System |
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361 | (22) |
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LORRAINE YAU AND PETER ZAHRADKA |
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28. Influence of the Myocardium Contractile State in the Coronary Venous Flow Deviation Phenomenon |
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383 | (10) |
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OTONI MOREIRA GOMES, ALFREDO INÁCIO FIORELLI, EROS SILVA GOMES, NELSON LUIZ TEIXEIRA BARROS-MORAES |
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29. Natriuretic Peptides and Endothelin in Aortic Stenosis and Heart Transplantation |
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393 | (12) |
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IGOR RIECANSKY, MARTIN VRSANSKY, KATARINA DANOVA, AND IVAN PECHAN |
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30. Activation of Mitogen-Activated Protein Kinases and Protein Kinase B/Akt Signaling by Oxidative Stress in Vascular Smooth Muscle Cells: Involvement in Vascular Pathophysiology |
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405 | (12) |
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ASHOK K. SRIVASTAVA, NIHAK R. PANDEM, AND ANTOINE BLANC |
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31. Preconditioning and Myocardial Angiogenesis |
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417 | (22) |
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32. The Arachidonic Acid Cascade: Thromboxane A2 Antagonism and Synthetase Inhibition in Experimental Myocardial Infarction |
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439 | (32) |
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SHIVA D. SETH, UMA SINGH, AND SANDESP SETH |
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| IV. NOVEL THERAPEUTIC APPROACHES TO CARDIOVASCULAR DISEASE |
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471 | (162) |
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33. Receptors and Channels of Nuclear Envelope Membranes as a New Target for Drug Action |
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473 | (12) |
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GHASSAN BKAILY, DANIELLE JACQUES, AND PEDRO D'ORLÉANS JUSTE |
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34. SMAD Cofactors/Corepressors in the Fibrosed Post-MI Heart: Possible Therapeutic Targets |
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485 | (28) |
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JULIE C. ROTH, BAIQIU WANG, DARREN H. FREED, AND IAN M.C. DIXON |
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35. Phytoestrogens and Cardiovascular Disorders |
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513 | (12) |
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RICKY Y.K. MAN, SUSAN W.S. LEUNG, HWEE TEOH, ADRIAN QUAN, WENDY KEUNG, AND MARY Y.K. LEE |
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36. Non-Conventional Long-Lasting Cardioprotection Induced by Chronic Exposure to Ambient Heat |
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525 | (10) |
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MICHAL HOROWITZ, OMER COHEN, YONATHAN HASILA, ALINA MALOYAN, AND EINAT LEVI |
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37. Fetal and Neonatal Cardiomyocyte Transplantation for the Treatment of Myocardial Infarction |
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535 | (10) |
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JOCHEN MÜLLER-EHMSEN, JONATHAN LEOR, LARRY KEDES, KIRK L. PETERSON, AND ROBERT A. KLONER |
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38. Cellular Cardiomyoplasty: The Role of Bone Marrow Stromal Cells in Myocardial Tissue Regeneration |
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545 | (10) |
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DEREK J. MACDONALD AND RAY C.-J. CHID |
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39. Xenotransplantation: An Overview |
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555 | (22) |
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RIZWAN A. MANDI, JACQUELINE S. MANDI, RAY V RAJOTTE, AND ARVIND KOSHAL |
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40. Assessment of Myocardial Injury Using Magnetic Resonance Imaging |
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577 | (20) |
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GANGHONG TIAN, JOHN MARK, BO XIANG, GUANGPING DAI, GANG LI, JIANKANG SUN, ROBERT CORNE, NORMAND LAZAROW, AND ROXANNE DESLAURIERS |
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41. Magnetic Resonance in the Assessment and Development of Surgical Strategies for Protecting the Brain During Cardiovascular Surgery |
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597 | (22) |
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JIAN YE, LUOJIA YANG, AND ROXANNE DESLAURIERS |
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42. Heart Failure Recovery with Mechanical Circulatory Support |
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619 | (14) |
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TOFY MUSSIVAND, PAUL HEERDT, KENNETH B. MARGULIES, O. HOWARD FRAZIER, GURMEET SINGH, AND HIDEO A. BABA |
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| Index |
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633 | |
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