Handbook of Bipolar Disorder: Diagnosis and Therapeutic Approaches,9780824729356

Handbook of Bipolar Disorder: Diagnosis and Therapeutic Approaches

by ;
Edition: 1st
ISBN13: 9780824729356
ISBN10: 0824729358
Format: Hardcover
Pub. Date: 2005-08-30
Publisher(s): CRC Press
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Summary

An expert summary of our current understanding of bipolar disorder, this reference examines existing theories, treatment regimens, and clinically relevant applications by world authorities in psychiatric research. Divided into four main sections, this guide delves into the diagnosis and epidemiology of bipolar disorder and progresses to discussions of patient care, emerging management approaches, and the underlying biology of the disease.

Table of Contents

Foreword iii
Frederick K. Goodwin
Preface v
Contributors xv
Concept of Bipolar Disorder: A Historical Perspective
1(10)
George N. Papadimitriou
Dimitris G. Dikeos
Constantin R. Soldatos
Introduction
1(1)
From Hippocrates to the Predecessors of Kraepelin
1(2)
The Era of Kraepelin and the First Half of the 20th Century
3(1)
Modern Classifications and Diagnostic Criteria
4(2)
Conclusions
6(1)
References
7(4)
Diagnosis of Bipolar Disorder
11(10)
Charles L. Bowden
Introduction
11(1)
Fundamental and Relatively Specific Symptoms and Illness Course Features of Bipolar Disorders
11(1)
Features of Depression Indicative of Bipolar Disorder
12(1)
Manic Symptoms with High Specificity and Sensitivity
13(1)
Effective Assessment Strategies for Bipolar Disorder
13(1)
Mania or Hypomania
14(2)
Depression
16(1)
Mixed States
17(1)
Involving the Patient and Family in Diagnosis
17(1)
References
17(4)
Epidemiology of Bipolar Disorder
21(16)
Zoltan Rihmer
Jules Angst
Introduction
21(2)
Prevalence and Incidence of Bipolar Disorders in the Community
23(4)
Demographic Factors
27(1)
Social Variables
28(1)
Psychosocial Stressors and Social Support
29(1)
Seasonal and Geographic Factors
30(1)
Comorbidity and Complications
30(1)
Public Significance of Bipolar Disorders
31(1)
References
31(6)
Re-examining the Bipolar-Schizophrenia Dichotomy
37(12)
Helmut Beckmann
Bruno Pfuhlmann
Kraepelin's Dichotomy and the Problem of ``Atypical'' Psychoses
37(1)
Concept of Cycloid Psychoses as a Solution of the Problem of ``Atypical'' Psychoses
38(1)
Symptomatology of Cycloid Psychoses
38(2)
Research Findings Regarding Cycloid Psychoses
40(4)
Conclusion: Cycloid Psychoses as a Challenge for the Bipolar-Schizophrenia Dichotomy
44(1)
References
45(4)
The Bipolar Spectrum: History, Description, Boundaries, and Validity
49(20)
Hagop S. Akiskal
Introduction
49(1)
The Concept of the Bipolar Spectrum
49(2)
Historical Roots
51(1)
Temperament in Bipolarity
52(1)
Description of the Bipolar Spectrum
53(3)
Do Recurrent ``Unipolar'' Depressions Belong to the Bipolar Spectrum (Type V)?
56(1)
Other Putative Bipolar Spectrum Conditions
56(1)
Critique of the Bipolar Spectrum
57(1)
Rates in Community and Clinical Populations
58(2)
Familial-Genetic Considerations
60(1)
Clinical Considerations
61(1)
Concluding Remarks
62(1)
References
63(6)
Bipolar Disorder in Children and Adolescents: Diagnosis, Epidemiology, and Clinical Course
69(14)
Nga Anh Nguyen
Karen Dineen Wagner
Introduction
69(1)
Epidemiology
70(1)
Diagnosis
70(3)
Differential Diagnosis and Comorbidity
73(4)
Course of Illness
77(1)
Conclusion
78(1)
References
78(5)
Bipolar Disorders in Late Life
83(12)
Peter Brieger
Andreas Marneros
Introduction
83(1)
Classification
84(2)
Clinical Presentation
86(1)
Epidemiology
87(1)
Course and Outcome
88(1)
Family History
89(1)
Neuroimaging
89(1)
Conclusion
90(1)
References
91(4)
Clinical Course in Bipolar Disorder
95(12)
Robert J. Boland
Martin B. Keller
Introduction
95(1)
Studying the Course of Bipolar Disorder
95(1)
Definition of Terms
96(1)
Overview of the CDS
96(7)
Conclusions and Future Directions
103(2)
References
105(2)
Recent Advances in Our Understanding of the Neurobiology of Bipolar Disorder
107(50)
Jorge A. Quiroz
Jaskaran Singh
Carlos A. Zarate Jr.
Husseini K. Manji
Introduction
107(1)
Monoaminergic Neurotransmitter Systems and Neuroendocrine Abnormalities
107(14)
Circadian Rhythms in the Pathophysiology and Treatment of Bipolar Disorder
121(2)
Evidence of HPA Hyperactivation Modulating Neural Plasticity
123(2)
Signaling Networks as Key Modulators of Long-Term Neuroplastic Events
125(6)
Abnormalities in Calcium Regulation and Mitochondrial Function in Bipolar Disorder
131(3)
Impairments of Neuroplasticity and Cellular Resilience in Bipolar Disorder
134(4)
Human Evidence for the Neurotrophic Effects of Mood Stabilizers
138(2)
Summary and Conclusions
140(1)
References
141(16)
Treatment of Mania
157(22)
John Cookson
Benefits of Treatment
157(1)
The Need for Admission
157(1)
Milieu Management
158(1)
Drug Treatment of Mania
158(14)
Treating Subtypes of Mania
172(1)
Conclusion
173(1)
References
174(5)
Bipolar Depression
179(12)
Robert M. A. Hirschfeld
L. A. Vornik
Introduction: Phenomenology, Diagnosis, and Clinical Course
179(1)
Bipolar Depression: Treatment Acute Pharmacotherapy
180(6)
Psychosocial Treatments
186(1)
Electroconvulsive Therapy
186(1)
Special Issues
187(1)
Conclusions and Recommendations
187(1)
References
188(3)
The Treatment of Mixed States
191(10)
Eduard Vieta
Jose Sanchez-Moreno
Introduction
191(2)
Treatment of Mixed States: General Rules
193(1)
Lithium
194(1)
Anticonvulsants
194(1)
Antipsychotics
194(2)
Electroconvulsive Therapy
196(1)
Conclusions
196(1)
References
197(4)
Rapid Cycling
201(12)
Andreas Erfurth
Giulio Perugi
Definition
201(1)
Epidemiological and Clinical Characteristics
202(1)
Family History, Genetics, and Rapid Cycling
203(1)
The Role of Antidepressants and of Other Treatments
203(1)
Thyroid Function and Rapid Cycling
204(1)
Rapid Cycling and the Female Reproductive Cycle
204(1)
Rapid Cycling and Biological Rhythms
205(1)
Pharmacological Treatment of Rapid Cycling
205(1)
Conclusions
206(1)
References
206(7)
Long-Term Mood Stabilization
213(14)
Zubin Bhagwagar
Guy M. Goodwin
Recurrence in Bipolar Disorder
213(1)
What Is a Mood Stabilizer?
214(1)
Pharmacological Treatment
214(4)
Suicide Prevention in Bipolar Disorder
218(1)
Psychological Interventions
219(2)
When to Start Long-Term Treatment and for Whom
221(1)
Conclusions
221(1)
References
222(5)
Schizoaffective Disorder
227(18)
Julio Bobes
Maria-Teresa Bascaran
Maria-Paz Garcia-Portilla
Pilar-Alejandra Saiz
Manuel Bousono
Gerardo Florez
Celso Arango
The Schizoaffective Dilemma
227(5)
The Treatment of Schizoaffective Disorder
232(7)
Conclusions
239(1)
References
239(6)
Treatment of Bipolar Disorder in Children and Adolescents
245(10)
Karen Dineen Wagner
Introduction
245(1)
Pharmacotherapy
245(5)
Electroconvulsive Therapy
250(1)
Psychoeducation
251(1)
Summary
251(1)
References
251(4)
Treatment of Bipolar Disorder in Late Life
255(12)
Mark Rapoport
Ayal Schaffer
Kenneth I. Shulman
Introduction
255(1)
Mood Stabilizers
256(3)
Antipsychotics
259(1)
Antidepressants
260(1)
Electroconvulsive Therapy
260(1)
Psychosocial Treatments
260(1)
Conclusion
261(1)
References
261(6)
Lithium in Bipolar Disorder
267(18)
Paul Grof
Introduction
267(1)
Historical Background
268(1)
Clinical Effects and Indications
269(4)
Adverse Effects of Lithium Treatment
273(3)
Special Situations
276(1)
Management of Lithium Treatment
277(2)
Putative Mechanisms of Action
279(1)
Summary
280(1)
References
280(5)
The Use of Anticonvulsants in the Treatment of Bipolar Disorder
285(30)
Paolo Brambilla
Jair C. Soares
Abstract
285(1)
Introduction
286(1)
First-Generation Anticonvulsants
286(11)
Second-Generation Anticonvulsants
297(6)
Conclusions
303(1)
References
303(12)
Atypical Antipsychotics in Bipolar Disorder
315(16)
Siegfried Kasper
Introduction
315(2)
Treatment of Mania
317(7)
Treatment of Bipolar Depression
324(2)
References
326(5)
Is There a Role for Typical Neuroleptics in Bipolar Disorder?
331(8)
H. J. Moller
Heinz Grunze
Introduction
331(1)
Use of Typical Neuroleptics in Routine Clinical Settings
332(1)
Evidence from Controlled Studies for the Efficacy of Typical Neuroleptics in Acute Mania
332(2)
Maintenance Treatment with Typical Neuroleptics in Bipolar Disorder
334(1)
Tolerability and Safety
334(2)
Conclusions
336(1)
References
336(3)
Antidepressants in Bipolar Disorder
339(18)
Lori Pellegrino
Jack Gorman
Introduction
339(1)
Current Guidelines on Antidepressant Use in Bipolar Disorder
339(1)
Efficacy in Bipolar Disorder vs. Unipolar Disorder
340(1)
Antidepressant Efficacy as Compared with Mood Stabilizer Efficacy
340(2)
The Switch to Mania
342(3)
Cycle Acceleration
345(1)
Types of Antidepressants
346(4)
Length of Antidepressant Treatment
350(1)
Conclusion
351(1)
References
352(5)
Combination Therapy in Bipolar Disorder
357(12)
Adrian J. Lloyd
Allan H. Young
Background
357(1)
Why Combine Treatment for Bipolar Disorder?
358(1)
Combination Treatments in Relation to Illness Subtype and Illness Phase
358(3)
Hazards of Combination Treatment
361(1)
Drug Combinations
362(2)
Summary
364(1)
References
364(5)
Expected Side-Effect Profile of Medications and Their Management
369(26)
John W. Newcomer
Nuri B. Farber
Dan Haupt
Peter Fahnestock
Introduction
369(1)
Side Effects of Lithium
370(3)
Side Effects of Antiepileptic Drugs Used for Bipolar Disorder
373(2)
Side Effects of Antipsychotic Medications Used for Bipolar Disorder
375(4)
Side Effects of Antidepressants for Bipolar Disorder
379(2)
Side Effects Associated with Metabolic Adverse Events
381(5)
Recommendations and Conclusion
386(1)
References
387(8)
Electroconvulsive Therapy in Bipolar Disorders and Other Brain Stimulation Methods: Vagus Nerve Stimulation, Transcranial Magnetic Stimulation, Magnetic Seizure Therapy and Deep Brain Stimulation
395(24)
M. Kosel
Thomas E. Schlaepfer
Introduction
395(1)
Electroconvulsive Therapy
396(3)
ECT as in the Treatment of Bipolar Disorders
399(4)
New Brain Stimulation Methods for Bipolar Disorders Under Research
403(8)
Discussion and Conclusions
411(1)
References
412(7)
Role of Psychotherapy in the Management of Bipolar Disorder
419(16)
Michael E. Thase
Introduction
419(1)
Background
419(4)
Review of Contemporary Treatment Strategies and Relevant Research
423(5)
Conclusions
428(2)
Acknowledgments
430(1)
References
430(5)
Toward an Integrated View: Algorithms in Bipolar Disorder
435(12)
Heinz Grunze
Introduction
435(1)
Strengths and Weaknesses of Guidelines for Bipolar Disorder
436(2)
The WFSBP Guidelines Series on the Treatment of Bipolar Disorder
438(3)
The British Association for Psychopharmacology Guideline
441(1)
Conclusions
442(1)
References
443(4)
Index 447

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