Global Burden of Disease And Risk Factors

by ; ; ; ; ;
Edition: 1st
Format: Hardcover
Pub. Date: 2006-04-02
Publisher(s): World Bank Publications
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Summary

Strategic health planning, the cornerstone of initiatives to facilitate the attainment of health goals in populations around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors, and the likely effects of proposed interventions. Critical to an effective assessment of risks and outcomes is a framework to integrate, validate, analyze, compare and disseminate available information to policy makers.

Table of Contents

Forewordp. xv
Prefacep. xvii
Editorsp. xix
Advisory Committee to the Editorsp. xxi
Contributorsp. xxiii
Disease Control Priorities Project Partnersp. xxv
Acknowledgmentsp. xxvii
Abbreviations and Acronymsp. xxix
Measuring the Global Burden of Disease and Risk Factors, 1990-2001p. 1
History of Burden of Disease Studiesp. 2
Applications of Burden of Disease Analysisp. 4
Improving the Comparative Quantification of Diseases, Injuries, and Risk Factors: The 2001 GBD Studyp. 5
Major Findings of the 2001 GBD Studyp. 7
Conclusionsp. 10
Referencesp. 11
Global Burden of Disease and Risk Factorsp. 15
Demographic and Epidemiological Characteristics of Major Regions, 1990-2001p. 17
Regional Demographic Characteristicsp. 18
Changes in Mortality, 1990-2001p. 21
Trends in Causes of Child Death, 1990-2001p. 28
Discussionp. 32
Conclusionsp. 35
Key Demographic Indicators, by Country/Territory, 1990 and 2001p. 36
Acknowledgmentsp. 43
Notesp. 43
Referencesp. 43
The Burden of Disease and Mortality by Condition: Data, Methods, and Results for 2001p. 45
Quantifying the Global Burden of Diseasep. 46
Estimating Deaths by Cause: Methods and Datap. 51
Global and Regional Mortality in 2001p. 68
Estimating Incidence, Prevalence, and YLD: Methods and Datap. 73
Burden of Disability and Poor Health in 2001p. 85
Global Burden of Disease in 2001p. 87
Discussion and Conclusionsp. 90
Definitions, Mortality Data Sources, and Disability Weightsp. 94
Deaths by Cause, Sex, Age, and Region, 2001p. 126
DALYs (3,0) by Cause, Sex, Age, and Region, 2001p. 180
Acknowledgmentsp. 234
Referencesp. 234
Comparative Quantification of Mortality and Burden of Disease Attributable to Selected Risk Factorsp. 241
Burden of Disease Attributable to Risk Factorsp. 242
Risk Factor Selectionp. 242
Burden of Disease Attributable to Individual Risk Factorsp. 247
Joint Effects of Multiple Risk Factorsp. 252
Burden of Disease Attributable to Multiple Risk Factorsp. 255
Directions for Future Researchp. 267
Discussionp. 267
Population Attributable Fractions, Attributable Deaths, Years of Life Lost Because of Premature Mortality (YLL), and Disability-Adjusted Life Years (DALYs) by Risk Factor, Disease Outcome, Age, Sex, and Regionp. 269
Referencesp. 394
Sensitivity Analysesp. 397
Sensitivity and Uncertainty Analyses for Burden of Disease and Risk Factor Estimatesp. 399
Discounting and Age Weighting in the DALY Measurep. 400
Sensitivity of Burden of Disease and Injury Results to Variations in Key Parameter Valuesp. 402
Sensitivity of Risk Factor Estimates to Variations in Key Parameter Valuesp. 406
Uncertainty Analysis of the Global Burden of Disease Estimatesp. 408
Uncertainty Estimates for All-Cause Mortality and Life Expectanciesp. 409
Uncertainty Estimates for Regional Mortality by Causep. 411
Uncertainty in Disability Weightsp. 413
Uncertainty Arising from Epidemiological Estimatesp. 417
Uncertainty in the Disease Burden Attributable to Risk Factorsp. 420
Discussionp. 423
Conclusionsp. 424
Acknowledgmentsp. 425
Referencesp. 425
Incorporating Deaths Near the Time of Birth into Estimates of the Global Burden of Diseasep. 427
Stillbirths and Neonatal Mortality in the Context of the Global Burden of Diseasep. 428
The Burden of Disease Resulting from Events Near the Time of Birthp. 431
Conclusionsp. 442
Flexible Functional Forms for the Acquisition of Life Potentialp. 442
Supplementary Tablesp. 445
Causes of Neonatal Mortality: Comparison of Numbers from the Global Burden of Disease with those from the Child Health Epidemiology Reference Groupp. 461
Acknowledgmentsp. 462
Referencesp. 462
List of Boxes
Disability-Adjusted Life Yearsp. 3
List of Figures
Overview of Burden of Disease Frameworkp. 2
Changes in Population Age Distribution, 1990-2001p. 22
Population Sex Ratios at Different Ages, 2001p. 23
UN's versus Authors' Life Table Parameters, 1990p. 24
Change in Risk of Death for Children Under Five by Cause (probability of mortality per 1,000 live births), 1990-2001p. 31
Relationship between Health Expectancies and Health Gaps in a Stationary Populationp. 47
Variation across Selected Countries in Coding for Ill-Defined CVD Causes, 1979-98p. 57
Mortality Rates for Socioeconomic Strata, by Cause Group, from China's Two Mortality Data Systemsp. 59
CodMod Estimation of Major Cause Group Proportional Mortality for Islamic Republic of Iran, 2001p. 61
Proportional Distribution of Total Deaths by Broad Cause Group, 2001p. 68
Death Rates by Broad Cause Group, Region, and Broad Age Group, 2001p. 69
Leading Causes of Premature Death (YLL) and of Deaths, Worldwide, 2001p. 73
Disease Model Underlying DisModp. 74
Input Prevalences and Incidence Rates Estimated Using DisMod II, for Diabetes Mellitus Cases in Males, Sub-Saharan Africap. 75
Life Expectancy, HALE, and Lost Healthy Years by Region and Sex, 2001p. 87
YLL, YLD, and DALYs by Region, 2001p. 87
Burden of Disease by Broad Cause Group and Region, 2001p. 88
Age Distribution of Burden of Disease by Income Group, 2001p. 89
Mortality and the Burden of Disease Attributable to Leading Global Risk Factors, by World Bank Regionp. 248
Burden of Disease Attributable to 10 Leading Regional Risk Factors, by Disease Typep. 251
Mediated and Direct Effects of a Risk Factorp. 253
Age-Weighting Function Incorporated into the DALYp. 401
Effect of Age Weighting and Discounting on the YLL per Death at Various Ages for Femalesp. 401
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