Diabetic Retinopathy

by
Edition: 1st
Format: Hardcover
Pub. Date: 2009-02-28
Publisher(s): Humana Pr Inc
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Summary

"Diabetic retinopathy is the most common microvascular complication of diabetes. It remains a major cause of new-onset visual loss in the United States and other industrialized nations. In Diabetic Retinopathy, Elia Duh and a panel of internationally recognized experts comprehensively assess the current state of knowledge regarding the clinical management of DR as well as its underlying mechanisms. The authors outline the current understanding of diabetic retinopathy from the perspective of clinical practice, while reviewing the multi-factorial pathogenesis and pathophysiology of DR from the standpoint of biomedical research. Also included is a discussion of emerging concepts relating to the management and treatment of DR. Informative and highly-practical, Diabetic Retinopathy provides ophthalmologists, diabetologists, endocrinologists, and internists with a highly readable guide not only to understanding diabetic retinopathy, but also to its optimal clinical management."--BOOK JACKET.

Table of Contents

Prefacep. v
Contributorsp. ix
Clinical Aspects of Diabetic Retinopathy
Nonproliferative Diabetic Retinopathyp. 3
Proliferative Diabetic Retinopathyp. 29
The Epidemiology of Diabetic Retinopathyp. 67
Diagnostic Modalities in Diabetic Retinopathyp. 109
Pathophysiology/Basic Research
In Vivo Models of Diabetic Retinopathyp. 137
Pathways of Hyperglycemia-induced Damage
The Polyol Pathway and Diabetic Retinopathyp. 159
The Role of Advanced Glycation in Diabetic Retinopathyp. 187
The Role of Protein Kinase C in Diabetic Retinopathyp. 207
Oxidative Stress in Diabetic Retinopathyp. 217
Pathophysiological Process in Diabetic Retinopathy
Pericyte Loss in the Diabetic Retinap. 245
Capillary Dropout in Diabetic Retinopathyp. 265
Neuroglial Dysfunction in Diabetic Retinopathyp. 283
The Role of Inflammation in the Pathophysiology of Diabetic Retinopathyp. 303
Vascular Permeability in Diabetic Retinopathyp. 333
Retinal Neovascularization and the Role of VEGFp. 353
Beyond VEGF - Other Factors Important in Retinal Neovascularization: Potential Targets in Proliferative Diabetic Retinopathyp. 375
Emerging Treatments and Concepts in Diabetic Retinopathy
Anti-VEGF Therapy as an Emerging Treatment for Diabetic Retinopathyp. 401
Clinical Trials in Protein Kinase C-[beta] Inhibition in Diabetic Retinopathyp. 423
The Role of Intravitreal Steroids in the Management of Diabetic Retinopathyp. 435
Antagonism of the Growth Hormone Axis as a Therapeutic Strategy for Diabetic Retinopathyp. 449
Diabetic Retinopathy and Systemic Complicationsp. 466
Name Indexp. 483
Subject Indexp. 489
Table of Contents provided by Ingram. All Rights Reserved.

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