Dermatopathology in Systemic Disease

by Smoller, Bruce R.; Horn, Thomas D.

ISBN13: 9780195130386

ISBN10: 0195130383

Format: Hardcover

Pub. Date: 2001-04-12

Publisher(s): Oxford University Press

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Summary

Dermatopathology of Systemic Disease provides extensive information on the cutaneous pathologic manifestations of systemic illnesses of all kinds. Written by a pathologist and dermatologist, the book offers an interdisciplinary perspective that suggests a series of diagnostic possibilities in the context of systemic symptoms not necessarily obvious from the cutaneous findings being evaluated. Organized by disease type (i.e. Connective tissue diseases, Metabolic and Storage Diseases, Drug-Induced Processes), the book is heavily illustrated with abundant color photomicrographs and clinical images. Clinical, histologic, and pathogenetic aspects of dermatopathology are discussed.

Part I Systemic Diseases Involving the Skin and Multiple Internal Organ Systems

Lupus Erythematosus

(14)

Discoid Lupus Erythematosus

(2)

Lupus Profundus

(1)

Systemic Lupus Erythematosus

(1)

Subacute Cutaneous Lupus Erythematosus

(1)

Neonatal Lupus Erythematosus

(1)

Antiphospholipid Syndrome

(1)

Bullous Lupus Erythematosus

(1)

Livedoid Vasculitis (Atrophie Blanche)

(1)

Miscellaneous

(5)

Connective Tissue, Joint Diseases, and the Skin

(20)

Dermatomyositis

(2)

Scleroderma

(1)

Progressive Systemic Sclerosis

(2)

Morphea

(1)

Acral Scleroderma

(1)

Eosinophilic Fasciitis

(1)

Mixed Connective Tissue Disease

(2)

Sjogren's Syndrome

(1)

Psoriasis and Arthritis

(4)

Rheumatoid Arthritis

(2)

Gout

(6)

Diabetes Mellitus

(10)

Necrobiosis Lipoidica Diabeticorum

(2)

Disseminated Granuloma Annulare

(1)

Bullosis Diabeticorum

(1)

Scleredema Diabeticorum

(1)

Diabetic Dermopathy

(1)

Eruptive Xanthomata

(1)

Yellow Skin

(4)

Vasculitis

(14)

Small-Vessel Vasculitides

(1)

Leukocytoclastic Vasculitis

(2)

Wegener's Granulomatosis

(1)

Churg-Strauss Allergic Granulomatosis

(1)

Behcet's Disease

(1)

Medium-Vessel Vasculitides

(9)

Polyarteritis Nodosa

(1)

Systemic (Classic)

(1)

Benign Cutaneous Polyarteritis Nodosa

(1)

Microscopic Polyarteritis Nodosa

(1)

Kawasaki's Disease (Mucocutaneous Lymph Node Syndrome)

(7)

Part II Diseases Involving the Skin and Limited Other Organ Systems

Gastrointestinal and Hepatic Diseases

(12)

Intestinal Disorders and Associated Cutaneous Diseases

(6)

Dermatitis Herpetiformis

(1)

Pyoderma Gangrenosum

(1)

Bowel-Associated Dermatitis/Arthritis Syndrome

(1)

Cutaneous Crohn's Disease

(1)

Degos' Disease (Malignant Atrophic Papulosis)

(1)

Peutz-Jehgers Syndrome

(1)

Hepatic Diseases and Associated Cutaneous Disorders

(2)

Porphyrias

(2)

Hemochromatosis

(1)

Pancreatic Diseases and Associated Cutaneous Disorders

(4)

Pancreatic Panniculitis

(4)

Pulmonary and Skin Diseases

(10)

Sarcoidosis

(2)

Lymphomatoid Granulomatosis

(1)

α1-Antitrypsin Deficiency

(1)

Cystic Fibrosis-Associated Dermatosis

(1)

Pachydermoperiostosis

(1)

Yellow Nail Syndrome

(5)

Cardiac and Skin Diseases

(9)

Amyloidosis

(2)

Carney's Complex

(2)

LEOPARD Syndrome

(1)

Cholesterol Emboli

(1)

Miscellaneous Conditions

(4)

Renal and Skin Diseases

(11)

Acute Renal Diseases

(4)

Henoch-Schonlein Purpura

(2)

Hemolytic Uremic Syndrome

(1)

Impetigo Contagiosa with Subsequent Post-Streptococcal Glomerulonephritis

(2)

Chronic Renal Disease

(7)

Calciphylaxis

(1)

Reactive Perforating Disorders of Diabetes and Renal Failure

(1)

Pruritus of Chronic Renal Failure

(1)

Half-and-Half Nails

(1)

Post-Transplant Lymphoproliferative Disorder

(4)

Diseases of the Nervous System and the Skin

103

(23)

Neurofibromatosis

103

(23)

Tuberous Sclerosis

108

(2)

Refsum's Syndrome

110

(1)

Sjogren-Larsson Syndrome

110

(1)

Rud's Syndrome

111

(1)

KID Syndrome

111

(1)

Vogt-Koyanagi-Harada Syndrome

112

(1)

Rubinstein-Taybi Syndrome

113

(1)

Myotonic Dystrophy

114

(1)

Sneddon's Syndrome

115

(1)

Hypomelanosis of Ito (Incontinentia Pigmenti Achromians)

116

(1)

Incontinentia Pigmenti

117

(9)

Hematologic Malignancies and Skin Diseases

126

(29)

Lymphomas

126

(8)

Large Cell Anaplastic Lymphoma

126

(2)

Angiocentric Lymphoma

128

(1)

Subcutaneous T-Cell Lymphoma (Histiocytic Cytophagic Panniculitis)

128

(2)

Intravascular Lymphoma (Malignant Angioendotheliomatosis)

130

(1)

Secondary B-Cell Lymphoma

131

(1)

Hodgkin's Disease Involving the Skin

132

(2)

Langerhans' Cell Proliffrations

134

(3)

Histiocytosis X

134

(2)

Indeterminate Cell Disorder

136

(1)

Leukemias and the Skin

137

(2)

Primary Leukemia Cutis

137

(1)

Secondary Leukemia Cutis

138

(1)

Plasma Cell Dyscrasias and Related Cutaneous Disorders

139

(4)

Multiple Myeloma

139

(1)

Extramedullary Plasmacytoma

139

(1)

Scleromyxedema

140

(2)

Other Mucocutaneous Conditions Associated with Multiple Myeloma

142

(1)

Waldenstrom's Macroglobulinemia

142

(1)

Miscellaneous Systemic Hematopoietic Proliferations in the Skin

143

(12)

Angioimmunoblastic Lymphadenopathy

143

(1)

Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease)

143

(2)

Cutaneous Eruptions of Lymphocyte Recovery

145

(10)

Musculoskeletal and Skin Diseases

155

(13)

Klippel-Trenaunay-Weber Syndrome

155

(1)

Maffucci's Syndrome and Ollier's Disease

156

(1)

Goltz's Syndrome (Focal Dermal Hypoplasia)

157

(1)

Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects (CHILD) Syndrome

158

(1)

Papillon-Lefevre Syndrome

159

(1)

Epidermal Nevus Syndrome

160

(2)

Buschke-Ollendorff Syndrome

162

(1)

Ehlers-Danlos Syndrome

163

(5)

Vascular Anomalies and Skin Diseases

168

(11)

Pseudoxanthoma Elasticum

168

(2)

Fabry's Disease

170

(1)

Osler-Weber-Rendu Disease (Hereditary Hemorrhagic Telangiectasia)

171

(1)

Blue Rubber Bleb Nevus Syndrome

172

(1)

Cobb's Syndrome

173

(1)

Sturge-Weber Syndrome

174

(1)

von Hippel-Lindau Disease

175

(4)

Endocrine Abnormalities and Skin Diseases

179

(12)

Pretibial Myxedema

179

(1)

Generalized Myxedema

180

(1)

Vitiligo

181

(1)

Mucosal Neuroma Syndrome

182

(1)

Necrolytic Migratory Erythema

183

(1)

Alopecia Areata

183

(2)

Addison's Disease

185

(6)

Part III Metabolic and Storage Diseases

Storage Diseases

191

(6)

Tangier Disease

191

(1)

Niemann-Pick Disease

191

(1)

Gaucher's Disease

192

(1)

Fucosidosis

193

(1)

Farber's Lipogranulomatosis

193

(4)

Hyperlipidemias and the Skin

197

(5)

Xanthomas

197

(3)

Xanthoma Disseminatum

200

(2)

Nutritional Imbalances and the Skin

202

(7)

Phrynoderma

202

(1)

Hypervitaminosis A

202

(1)

Scurvy

203

(1)

Pellagra

203

(1)

Hartnup's Disease

204

(1)

Richner-Hanhart Syndrome (Type II Oculotyrosinosis)

204

(1)

Kwashiorkor

205

(4)

Part IV Infectious Diseases and the Skin

Bacterial Diseases

209

(21)

Direct Bacterial Infections

209

(12)

Meningococcemia

209

(1)

Septic Vasculitis/Emboli

209

(1)

Syphilis

210

(3)

Lyme Disease

213

(2)

Mycobacterial Infections-Tuberculosis

215

(2)

Mycobacterium Other than tuberculosis

217

(1)

Leprosy

218

(3)

Sequelae

221

(9)

Erythema Induratum

221

(1)

Papulonecrotic Tuberculid

222

(1)

Lichen Scrofulosorum

222

(1)

Toxic Shock Syndrome

223

(1)

Staphylococcal Scalded Skin Syndrome

224

(6)

Viral Diseases

230

(21)

Direct Infection

230

(12)

Human Papillomavirus

230

(3)

Herpes Viruses

233

(2)

Cytomegalovirus

235

(1)

Molluscum Contagiosum

236

(1)

Human Immunodeficiency Virus

237

(5)

Secondary Manifestations of Viral Infection

242

(9)

Papular Acrodermatitis of Childhood (Gianotti-Crosti Syndrome)

242

(1)

Hepatitis C

243

(8)

Fungal and Algal Diseases

251

(15)

Aspergillosis

251

(1)

Zygomycosis (Mucormycosis)

252

(1)

Cryptococcosis

253

(2)

Histoplasmosis

255

(1)

Blastomycosis (North American)

255

(2)

Coccidioidomycosis

257

(1)

Protothecosis

257

(1)

Related Hypersensitivity Reactions

258

(1)

Erythema Annulare Centrifugum

258

(1)

Id (Autosensitization Reaction) Reaction

259

(1)

Erythema Nodosum

260

(6)

Rickettsial Diseases

266

(4)

Rocky Mountain Spotted Fever

266

(1)

Ehrlichiosis

267

(1)

Rickettsialpox

268

(2)

Parasitic Infestations

270

(7)

Leishmaniasis

270

(1)

Acanthamebiasis

271

(6)

Part V Drug-Induced Processes

Drug-Induced Autoimmune Eruptions

277

(7)

Pemphigus

277

(2)

Pemphigoid

279

(2)

Linear IgA Bullous Dermatosis

281

(3)

Drug-Induced Interface Dermatoses

284

(10)

Erythema Multiforme

284

(2)

Toxic Epidermal Necrolysis

286

(2)

Fixed Drug Eruption

288

(1)

Drug-Induced Lupus Erythematosus

289

(1)

Lichenoid Drug Eruptions

290

(4)

Photo-Related Drug Eruptions

294

(4)

Phototoxic Drug Eruptions

294

(1)

Photoallergic Drug Eruptions

295

(3)

Chemotherapy-Induced Drug Eruptions

298

(6)

Neutrophilic Eccrine Hidradenitis

298

(1)

Neutrophilic Dermatosis Associated with Granulocyte-Macrophage and Granulocyte Colony-Stimulating Factor

299

(1)

Acral Erythema

300

(1)

Syringosquamous Metaplasia

301

(3)

Miscellaneous Drug Eruptions

304

(7)

Acute Generalized Exanthematous Pustulosis

304

(1)

Drug-Induced Pseudolymphomas

305

(6)

Part VI Internal Malignant Neoplasms and Skin Diseases

Cutaneous Neoplasms and Cysts Associated with Internal Malignancy

311

(10)

Muir-Torre Syndrome

311

(3)

Cowden's Syndrome (Multiple Hamartoma and Neoplasia Syndrome)

314

(2)

Gardner's Syndrome

316

(1)

Birt-Hogg-Dube Syndrome

317

(4)

Epidermal Proliferative Processes Associated with Internal Malignancy

321

(7)

Acanthosis Nigricans

321

(2)

Bazex's Syndrome (Acrokeratosis Paraneoplastica)

323

(1)

Acquired Ichthyosis

323

(1)

Leser-Trelat Syndrome

324

(4)

Histiocytic Proliferations and Internal Malignancy

328

(6)

Necrobiotic Xanthogranuloma with Paraproteinemia

328

(2)

Multicentric Reticulohistiocytosis

330

(1)

Normolipemic Planar Xanthoma

331

(3)

Miscellaneous Cutaneous Lesions

334

(9)

Paraneoplastic Pemphigus

334

(1)

Erythema Gyratum Repens

335

(1)

Superficial (Migratory) Thrombophlebitis

336

(1)

Paraneoplastic Vasculitis

337

(1)

Sweet's Syndrome (Acute Febrile Neutrophilic Dermatosis)

337

(2)

Pityriasis Rotunda

339

(4)

The Skin and Metastatic Diseases

343

(8)

Part VII Pediatric Diseases with Prominent Cutaneous Features

Congenital Disorders

351

(24)

Down's Syndrome

351

(2)

Rothmund-Thomson Syndrome

353

(1)

Bloom's Syndrome

354

(1)

Ataxia-Telangiectasia

355

(1)

Progeria

356

(1)

Albinism

356

(1)

McCune-Albright Syndrome

357

(1)

Waardenburg's Syndrome

358

(1)

Xeroderma Pigmentosa

358

(2)

Cockayne's Syndrome

360

(1)

Dyskeratosis Congenita

360

(1)

Proteus Syndrome

361

(1)

Basal Cell Nevus Syndrome (Gorlin's Syndrome)

362

(1)

Lipoid Proteinosis (Hyalinosis Cutis et Mucosae)

363

(1)

Epidermolysis Bullosa

364

(1)

Congenital Nevus (Giant)

365

(10)

Index

375

Dermatopathology in Systemic Disease

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