Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials

by ; ; ;
Edition: 1st
Format: Hardcover
Pub. Date: 2007-08-03
Publisher(s): Springer Verlag
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Summary

This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound, which provide not only 2-D and 3-D images of the related organs or tissues, but also quantifications of the relevant parameters. The advance bioimaging technologies developed for the above applications are also extended by incorporating imaging contrast-enhancement materials. Thus, this book will provide a unique platform for multidisciplinary collaborations in education and joint R&D among various professions, including biomedical engineering, biomaterials, and basic and clinical medicine.

Table of Contents

Perspectives of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies and Applications
Advances in Assessment of Quality of Bone and Orthopaedic Applications
Perspectives on Advances in Bone Imaging for Osteoporosisp. 5
Bone Structure and Biomechanical Analyses Using Imaging and Simulation Technologyp. 27
Imaging Technologies for Orthopaedic Visualization and Simulationp. 51
In-Vivo Bone Mineral Density and Structures in Humans: From Isotom Over Densiscan to Xtreme-CTp. 65
Calibration of Micro-CT Data for Quantifying Bone Mineral and Biomaterial Density and Microarchitecturep. 79
Repositioning of the Region of Interest in the Radius of the Growing Child in Follow-up Measurements by pQCTp. 85
Non-invasive Bone Quality Assessment Using Quantitative Ultrasound Imaging and Acoustic Parametersp. 103
Advances Microscopic Technologies and Applications
Cortical Bone Mineral Status Evaluated by pQCT, Quantitative Backscattered Electron Imaging and Polarized Light Microscopyp. 135
High-Fidelity Histologic Three-Dimensional Analysis of Bone and Cartilagep. 163
Application of Laser Scanning Confocal Microscopy in Musculoskeletal Researchp. 173
Fiber-optic Nano-biosensors and Near-Field Scanning Optical Microscopy for Biological Imagingp. 191
Changes of Biological Function of Bone Cells and Effect of Anti-osteoporosis Agents on Bone Cellsp. 205
Bone Histomorphometry in Various Metabolic Bone Diseases Studied by Bone Biopsy in Chinap. 223
Cell Traction Force Microscopyp. 227
Advances in Vascular Research and Applications
Contrast-Enhanced Micro-CT Imaging of Soft Tissuesp. 239
Advances in Scaffold Biomaterial Research and Applications
Materials Selection and Scaffold Fabrication for Tissue Engineering in Orthopaedicsp. 259
Quantification of Porosity, Connectivity and Material Density of Calcium Phosphate Ceramic Implants Using Micro-Computed Tomographyp. 289
Bone Densitometries in Assessing Bone Mineral and Structural Profiles in Patients with Adolescent Idiopathic Scoliosisp. 307
Application of Nano-CT and High-Resolution Micro-CT to Study BoneQuality and Ultrastructure, Scaffold Biomaterials and Vascular Networksp. 323
Bio-imaging Technologies in Studying Bone-Biomaterial Interface: Applications in Experimental Spinal Fusion Modelp. 331
Assessment of Bone, Cartilage, Tendon and Bone Cells by Confocal Laser Scanning Microscopyp. 351
Specific Applications of Advances in Musculoskeletal and Scaffold Biomaterial Imaging Technologies
In Assessment of Osteoporosis and Treatment
TEM Study of Bone and Scaffold Materialsp. 371
Material and Structural Basis of Bone Fragility: A Rational Approach to Therapyp. 391
Application of Micro-CT and MRI in Clinical and Preclinical Studies of Osteoporosis and Related Disordersp. 397
CT-Based Microstructure Analysis for Assessment of Bone Fragilityp. 415
Discrimination of Contributing Factors to Bone Fragility Using vQCT In Vivop. 429
Osteoporosis Research with the vivaCT40p. 449
Mechanical Properties of Vertebral Trabeculae with Ageing Evaluated with Micro-CTp. 461
MRI Evaluation of Osteoporosisp. 473
Multiple Bio-imaging Modalities in Evaluation of Epimedium-Derived Phytoestrogenic Fraction for Prevention of Postmenopausal Osteoporosisp. 483
Areal and Volumetric Bone Densitometry in Evaluation of Tai Chi Chuan Exercise for Prevention of Postmenopausal Osteoporosisp. 503
Enhancement of Osteoporotic Bone Using Injectable Hydroxyapatite in OVX Goats Evaluated by Multi-imaging Modalitiesp. 515
In Assessment of Fracture Repair
Quality of Healing Compared Between Osteoporotic Fracture and Normal Traumatic Fracturep. 529
Monitoring Fracture Healing Using Digital Radiographiesp. 541
Fracture Callus Under Anti-resorptive Agent Treatment Evaluated by pQCT p. 551
In Assessment of Osteonecrosis
Volumetric Measurement of Osteonecrotic Femoral Head UsingComputerized MRI and Prediction For Its Mechanical Propertiesp. 567
Biomedical Engineering in Surgical Repair of Osteonecrosis: the Role of Imaging Technologyp. 577
Contrast-Enhanced MRI and Micro-CT Adopted for Evaluation of a Lipid-Lowering and Anticoagulant Herbal Epimedium-Derived Phytoestrogenic Extract for Prevention of Steroid-Associated Osteonecrosisp. 591
Nanomechanics of Bone and Bioactive Bone-Cement Interfacesp. 611
In Assessment of Osteoarthritis
Subchondral Bone Microarchitecture Changes in Animal Models of Arthritisp. 627
Microarchitectural Adaptations of Primary Osteoarthrotic Subchondral Bonep. 641
Ultrasonic Characterization of Dynamic Depth-Dependent Biomechanical Properties of Articular Cartilagep. 657
Mechanical PropertyofTrabecular Bone of the Femoral Heads from Osteoarthritis and Osteoporosis Patientsp. 673
Indexp. 691
Table of Contents provided by Publisher. All Rights Reserved.

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